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All these electrical signals encode the sound, and the signal travels up the nerve to the brain. These movements trigger the hair cells to release neurotransmitters that cause an electrical signal in the neurons of the cochlear nerve. Inside the fluid-filled cochlea, a membrane ripples in response to sound vibrations, and those ripples move bundles of sensory hair cells that project from the surface of that membrane. Those bones transfer the vibrations to the inner ear’s cochlea, a snail-shaped structure about the size of a pea. In a functioning human ear, sound waves are channeled down the ear canal and set the ear drum in motion, which in turn vibrates tiny bones in the middle ear. To understand why, you first need to understand how natural hearing works. Yet they make limited use of the neurons available for sound encoding in the cochlea. Nearly 737,000 devices had been implanted globally by 2019.
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Food and Drug Administration in the 1980s, and The first device was approved by the U.S. Today’s cochlear implants are the most successful neuroprosthetic to date. In the 2030s, people all over the world could begin to hear the light. Profoundly hearing-impaired people benefit more from cochlear implants, which, as mentioned above, skip over dysfunctional or lost hair cells and directly stimulate the cochlear, or auditory, nerve. Hearing can be partially restored by hearing aids, which essentially provide an amplified version of the sound to the remaining sensory hair cells of the cochlea. Hearing loss mainly results from damage to the cochlea caused by disease, noise, or age and, so far, there is no cure.
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Daniel Keppeler How cochlear implants workĤ66 million people worldwide suffer from disabling hearing loss that requires intervention, according to the World Health Organization. In the middle and right images, the bony housing of the mouse cochlea surrounds this delicate arrangement. At left, the hair cells connect to the cochlear nerve cells. These 3D microscopic images of mouse ear anatomy show optical implants twisting through the intricate structure of a normal cochlea, which contains hair cells in deafness, these cells are lost or damaged. Then, people all over the world could begin to hear the light. We aim to start clinical trials in 2026 and, if all goes well, we could get regulatory approval for our device at the beginning of the next decade.
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By using precise beams of light instead of electrical current to stimulate the cochlear nerve, we expect our optical cochlear implants to better replicate the full spectral nature of sounds and better mimic natural hearing. So we’re developing a new kind of cochlear implant that uses light emitters and genetically altered cells that respond to light. We recognize that today’s cochlear implants run up against hard limits of engineering and human physiology. For 15 years, my team at the University of Göttingen, in Germany, has been collaborating with colleagues at the University of Freiburg and beyond to reinvent the cochlear implant in a strikingly counterintuitive way: using light.
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My patients tell me they want more natural sound, more enjoyment of music, and most of all, better comprehension of speech, particularly in settings with background noise-the so-calledĬocktail party problem. I have been an otolaryngologist for more than two decades. Although users can have many sessions with technicians to “tune” and adjust their implants’ settings to make sounds more pleasant and helpful, there’s a limit to what can be achieved with today’s technology. When my hearing-impaired patients have their cochlear implants turned on for the first time, they often report that voices sound flat and robotic and that background noises blur together and drown out voices. A cochlear implant bypasses the damaged or dysfunctional parts of the ear and uses electrodes to directly stimulate the cochlear nerve, which sends signals to the brain. Natural hearing results from vibrations hitting tiny structures called hair cells within the cochlea in the inner ear.
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In fact, these marvels of engineering give people a new kind of “electric hearing” that they must learn how to use. There’s a popular misconception that cochlear implants restore natural hearing.
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